Africa & Science – Afrika & Wissenschaft – Afrique & Science

Nr. 00265- 9th Jan. 2024 – Weekly Newspaper devoted to Science & Technology in Africa ** Pour la promotion de l'esprit scientifique en Afrique

Regenerative Medicine

The Löwenheim group is located at the University of Tübingen Medical Centre, Department of Otolaryngology, Head & Neck Surgery. The group has exclusive access to laboratories for biochemical, cell biological, molecular-biological and physiological work. There are three rooms equipped with biosafety cabinets for cell and organ culture, several shared central equipment core rooms, and two audio booths for small animals fully equipped for sophisticated auditory electrophysiology. There are three fluorescence microscopes (one LSM) exclusively used by the Löwenheim group. There is access to LSM, TEM and SEM electron microscopes located anatomical department of the University of Tübingen. Animal care facility (SPF) is located within the building. The medical school Tübingen has several core facilities, including DNA sequencing, microarray, laser dissection, FACS, PET, MET, Proteomics and transgenic mouse facility.

The group has established several inner ear assay platforms: murine inner ear derived cell lines, cochlear progenitor cell expansion, in vitro cochlea spiral ganglion cell model, in vitro culture model for the whole inner ear for drug screening; in vivo hearing loss models and local drug application technology.

Senior staff:

Prof. Dr. med. Hubert Löwenheim, Leader of the project team “Regenerative Medicine” at the Tübingen Hearing Research Center, Stellvertretender Ärztlicher Direktor, Klinik für Hals-, Nasen- und Ohrenheilkunde Tübingen.

Priv.-Doz. Dr. phil. nat. Marcus Müller, Senior scientist with too many years of experience in various in vivo animal models, inner ear local drug application technology, and functional assessment of the inner ear in birds and mammals.

Research Interest

  • Regeneration in the inner ear
  • Stem cell research
  • Water regulation in the inner ear
  • Treatment of noise induced hearing loss
  • Protection of hair cell loss after acoustic or ototoxic trauma
  • Development of organ culture methods to reduce animal experiments
  • Improvement of cochlear implant performance

National and international scientific partners

http://thrc.hno.medizin.uni-tuebingen.de/groups/home

Fero and Roberts, Fred Hutchinson Cancer Research Center, Seattle USA
Gharabaghi, Klinik für Neurochirurgie am Universitätsklinikum Tübingen
Kumagami, Nagasaki University, Japan
Heller, Stanford University, Stanford USA

Professor Dr. med. Hubert Löwenheim

Department of Otolaryngology, Head and Neck Surgery

Tübingen Hearing Research Centre
Elfriede-Aulhorn-Strasse 5
D-72076 Tübingen
Germany

Phone: +49 (0)7071/29-88088
Fax: +49 (0)7071/29-3311
hubert.loewenheim@uni-tuebingen.de

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